20 players return to the girls’ basketball courts for the 2021-22 campaign after earning either first or second team all-state honors last season.
CLASS 1A
| Whitney Chintala | Fleming | 1st Team |
| Kenlee Durrill | Flatirons Academy | 1st Team |
| Kylie Krise | Briggsdale | 1st Team |
CLASS 2A
| Karly Godsey | Wray | 1st Team |
| Trista Marx | Limon | 1st Team |
| Kristin Vieselmeyer | Holyoke | 1st Team |
| Asia Caldon | Sanford | 2nd Team |
| Lauren Herman | Holyoke | 2nd Team |
| Michiah Leeper | Limon | 2nd Team |
CLASS 3A
| Julianna Garcia | Vanguard | 1st Team |
| Raelyn Kelty | Lutheran | 1st Team |
| Cora Schissler | Platte Valley | 1st Team |
| Brooke Bunting | Platte Valley | 2nd Team |
| Ramiyah Byrd | Vanguard | 2nd Team |
CLASS 4A
| Gracie Gallegos | Mullen | 1st Team |
| Olivia Reed | Windsor | 1st Team |
| Jayda Mayes | Green Mountain | 2nd Team |
| Grace Moyers | Erie | 2nd Team |
CLASS 5A
| Lauren Betts | Grandview | 1st Team |
| Sam Crispe | Arapahoe | 2nd Team |
NOTE: Raegan Beers of Valor Christian was first team selection for the 2019-20 season and missed all of last year with an injury but returns for this season.