While Roosevelt and Holy Family are two wins away from winning a second straight state title in their respective 5A and 4A girls’ basketball classifications, there will be a new champ in 6A.

Two-time defending champ Grandview’s second-round exit in the state’s biggest class leaves the door open for a first program title for either Cherokee Trail or Legend, or a fourth for Valor Christian or Regis Jesuit.

The Final Four for all three classes run Thursday-Friday, with the finals to follow Saturday. All games will be played at the Denver Coliseum.

Class 6A

No. 1 Cherokee Trail vs. No. 4 Valor Christian; Thursday at 5:45 p.m.: Damara Allen (11.6 PPG) has 30 points and nine steals in three postseason games for the Cougars (24-2).

Quinn Vansickle (18.3 PPG) has 45 points in these playoffs for the Eagles (21-4), who beat Cherokee Trail in their only-ever matchup in 2013.

In the quarterfinals, Cherokee Trail held No. 9 Mullen to three points in the third quarter in a 47-39 win. The round before, the Mustangs beat Grandview.

Valor Christian, meanwhile, beat its first three playoff opponents by an average of 27 points.

No 3 Legend vs. No. 7 Regis Jesuit; Thursday at 7:15 p.m.: The Raiders (19-7) had beaten the Titans 13 straight times before Legend’s 68-53 win Feb. 16.

Hana Belibi (17.5 PPG, 8.5 RPG) has 48 points and 36 rebounds this postseason for Regis Jesuit. Mason Borcherding (12.2, 7.9) has 36 and 19 for Legend (24-2).

In the quarterfinals, Regis Jesuit upset No. 2 Cherry Creek behind 17 points from Coryn Watts (16.2 PPG), and 11 and 13 from Belibi.

The Titans beat Horizon by 27, led by Maley Willhelm’s 13 points on 6-of-12 shooting.

Class 5A

No. 1 Air Academy vs. No. 4 Northfield; Thursday at 11 a.m.: The Kadets (25-1) had to rally from a nine-point halftime deficit to top No. 8 Frederick in the quarterfinals.

Their leading scorer, Caitlin Kramer (19.6 PPG) had 15 points in that win, and has averaged 15.3 PPG this postseason.

Freshmen Madison Bethel (12.5 PPG) and Laporsha Allen (10.8 PPG, 5.8 RPG) continue to lead the Nighthawks (23-3) in the playoffs, with Bethel scoring 44 points on 55% shooting in three games, and Allen with 54 points and 18 boards.

This is the first meeting between the two programs.

No. 2 Roosevelt vs. No. 3 Mead; Thursday at 2:15 p.m.: Roosevelt (24-2) leads the series 12-6 dating back to 2013.

The Roughriders have had little trouble through the first three rounds, beating No. 31 Falcon and No. 18 Northridge by 30, then No. 7 Montrose by 15.

Going for their second straight title, they’ll need to overcome Mead (22-4), a team back in the Final Four for a second time in three seasons.

Leading the Mavs, Darby Haley (11.4 PPG) has been sensational. In a 13-point, fourth-quarter comeback over No. 14 Mountain View in Round 2, she had 25 points, five assists and six steals.

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Class 4A

No. 1 Holy Family vs. No. 4 Resurrection Christian; Friday at 2:15 p.m.: The Tigers (24-2) have won by an average of 50.3 PPG in this postseason.

The Cougars (23-3) won by 60 in Round 1, then 34 and nine the next two.

This should be tighter.

Essynce Contreraz (11.6 PPG) can light it up at any time for Holy Family. A leading scorer during last year’s finals run, too, she had 26 points on 10-of-15 shooting in her latest 4A Sweet 16.

Olivia Klein (16.7 PPG) has scored 18, 20 and 18 in her three postseason games for Rez. She will be the focal point for the Tigers coach Ron Rossi’s gritty defense.

Holy Family is 2-0 against Rez all-time per MaxPreps, beating the Cougars 56-50 on Dec. 8.

No. 2 D’Evelyn vs. No. 3 Riverdale Ridge; Friday at 11 a.m.: With Sienna Betts and Grandview out in 6A, Riverdale Ridge sophomore Brihanna Crittendon (29.3 PPG, 10.7 RPG) is the best prospect left in the girls’ basketball postseason.

To continue a decorated career, she’ll need to get by a player with one of her own in Peyton Marvel (18.9 PPG, 13.5 RPG).

Crittendon has 77 points in this postseason for the Ravens (23-3), who edged No. 14 TCA in the second round before beating No. 6 Colorado Academy by 31 in the quarterfinals.

Marvel had 23 points and 15 rebounds in the quarters for the Jaguars (23-3), beating No. 7 University 55-39.

The Jags beat RR in last year’s Great Eight and went on to the finals, where they lost to Holy Family.